Search Results - assaf+zinger

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Leukocyte-Derived Nanoparticles to Treat Triple-Negative Breast Cancer

This invention is an engineered biomimetic lipid-based nanoparticle (NP) functionalized with leukocyte membrane proteins (a.k.a. leukosomes) which are capable of targeting vascular inflammation. The ratio at which these leukocyte proteins are integrated within the NP shell dictates the biological behavior of the leukosomes. This particular formulation...

Published: 3/12/2024 | Inventor(s): Francesca Taraballi, Assaf Zinger

Keywords(s):

Category(s): Clinical Area > Cancer, Research Area > Cancer, Research Area > Nanomedicine, Technology Classifications > Therapeutic > Drug Delivery, Technology Classifications > Therapeutic > Nanovesicles

Neural/Glial Cell-Derived Nanoparticles to Restore Neural Function in Alzheimer’s Disease

This invention is an engineered biomimetic nanoparticle (NP) that integrates neural or glial cell membrane proteins into lipid-based nanoparticles (a.k.a. neurosomes). The integration of these neural/glial cell proteins within the NP shell enable precise targeting to treat a variety of neurological disorders resulting from trauma, neurodegeneration,...

Published: 3/12/2024 | Inventor(s): Robert Krencik, Assaf Zinger, Ennio Tasciotti, Caroline Cvetkovic

Keywords(s):

Category(s): Technology Classifications > Therapeutic > Drug Delivery, Technology Classifications > Therapeutic > Nanovesicles, Clinical Area > Neurology, Research Area > Neurology and Neurosurgery, Research Area > Nanomedicine