Search Results - john+cooke

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Method for Vascular Regeneration and Wound Treatment

Asset/Technology Type Therapeutic Strategy Description of Invention The invention is a therapeutic approach for modulating cellular trans-differentiation and potentially angiogenesis by modulating O-glcnacylation (GlcNAc) of proteins, to treat various conditions. The inventors used existing small molecules to prove the concept in vitro and in vivo....

Published: 4/2/2025 | Inventor(s): John Cooke, Li Lai

Keywords(s):

Category(s): Clinical Area, Clinical Area > Cardiovascular, Research Area > Heart and Vascular, Research Area > Regenerative Medicine, Technology Classifications, Technology Classifications > Other

Glycolytic Modulators for Therapeutic Regulation of Cell Fate

This invention is a glycolysis enhancement strategy using glycolytic modulators to improve cell fate transitions. Applied topically, systemically, or in combination with a biocompatible scaffold, the glycolytic enhancers are expected to improve wound healing, vascularity, and tissue regeneration as well as reduce fibrosis. In another application, a...

Published: 3/12/2024 | Inventor(s): John Cooke, Li Lai

Keywords(s):

Category(s): Technology Classifications > Therapeutic > Small Molecules, Research Area > Regenerative Medicine, Clinical Area > Cancer, Research Area > Cancer