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Aptamer-Based Assay for Rapid Detection of Mycoplasma-infected cells

The technology is an aptamer-based reagent for rapid detection mycoplasma-infected cultured and primary cells for biomedical study and clinical uses.Stage of Development In vitro data: Flow cytometry analysis showed that the synthetic aptamer probes selectively bind to mycoplasma-infected cultured and primary human cells. The aptamer probes can specifically...

Published: 3/12/2024 | Inventor(s): Youli Zu

Keywords(s):

Category(s): Technology Classifications > Diagnostic, Technology Classifications > Research Tool > In Vitro Diagnostics, Clinical Area > Infectious Disease

Aptamer-engineered Natural Killer Cells for Adaptive Immunotherapy

The invention is a unique technology to engineer Natural Killer (NK) cells with synthetic oligonucleotide aptamers for tumor cell-specific cancer immunotherapy. Stage of Development In vitro Study: The aptamer-engineered NK (ApEn-NK) cells could be generated via a simple one-step process in minutes. The generated ApEn-NK cells were able to specifically...

Published: 10/7/2024 | Inventor(s): Youli Zu

Keywords(s):

Category(s): Clinical Area > Cancer, Research Area > Cancer, Clinical Area > Metabolic Disease, Inflammation, and Immunology, Technology Classifications > Therapeutic > Cell and Gene Therapies