|
Specific PD-1 DNA Aptamers as Immunotherapeutic Agents in the Treatment of Cancers
The invention are therapeutic PD-1 DNA aptamers used to block PD-1 activity and enhance T-cell cytotoxicity against leukemias and solid tumors. Stage of Development In vitro data: Several aptamers were developed using SELEX technology against endogenous immunoprecipitated PD-1 and they were found to have highly conserved regions using high throughput...
Published: 3/12/2024
|
Inventor(s): Swaminathan Iyer, Santhana Thankgavelu Devaraj
Keywords(s):
Category(s): Clinical Area > Cancer, Research Area > Cancer, Technology Classifications > Therapeutic > Immunotherapy
|
