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Microfibrillar-associated Protein 5 (MFAP5)-Specific Monoclonal Antibodies as Therapeutic Agents in Ovarian and Pancreatic Cancers
The invention are therapeutic monoclonal antibodies directed against microfibrillar-associated fibroblast-derived secreted protein 5 (MFAP-5) for the treatment of ovarian and pancreatic cancer. Cancer associated fibroblasts (CAFs) in the tumor stromal microenvironment exhibit altered secretion of extracellular proteins, which modify the tumor environment...
Published: 10/1/2024
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Inventor(s): Stephen Wong, Jianting Sheng, Tsz Lun Yeung, Sze Lee Cecilia Leung, Samuel Mok
Keywords(s):
Category(s): Clinical Area > Cancer, Research Area > Cancer, Technology Classifications > Therapeutic > Antibodies
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