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Invention The invention consists of novel compounds for angiogenesis-targeted therapy and imaging particularly for diseases such as cancer where increased angiogenesis is deleterious. The compounds target the VEGF receptor (VEGFR) with 100-fold improvement in binding affinity, higher specificity and tumor cell uptake and improved blood clearance. The...

Published: 5/18/2020 | Inventor(s):

Keywords(s):

Category(s): Technology Classifications > Medical Imaging, Technology Classifications > Therapeutic

Sustained delivery of doxorubicin to tumors

Invention The invention provides an efficient and sustained release of doxorubicin in a tumor. The invention is a polymer linked to doxorubicin, packaged inside a porous particle. High local concentrations of doxorubicin can be achieved at the site of the tumor which avoids the toxic effects of the drug on other tissues. Other cancer drugs may be attached...

Published: 3/12/2024 | Inventor(s):

Keywords(s):

Category(s): Technology Classifications > Therapeutic